MSL2

Across TCGA patient cohorts, MSL2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,192 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MSL2-associated genes across cancer lineages are UMPS, NEPRO, and RYK. Each is linked with MSL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MSL2-to-partner and partner-to-MSL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSL2 versus UMPS in LSCC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSL2→partner) and Y-score (partner→MSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UMPS →	+0.757	+0.457	<.001	<.001	3	4
LSCC	NEPRO →	+0.505	+0.395	<.001	<.001	3	4
LSCC	RYK →	+0.689	+0.432	<.001	<.001	3	4
OV	RPL35AP36 →	+1.308	+0.401	.009	.004	3	3
OV	EIF1AXP1 →	+1.277	+0.462	<.001	<.001	3	3
LSCC	TEX10 →	+0.570	+0.392	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,192 associations by consensus.

MSL2 vs UMPS — LSCC

Explore this scatter interactively →