Across TCGA cell cohorts, MSL1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MSL1-associated genes across cancer lineages are TCP10L2, OR10A4, and CCL16. Each is linked with MSL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSL1-to-partner and partner-to-MSL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSL1→partner) and Y-score (partner→MSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TCP10L2 →	+0.091	+4.217	<.001	.005	3	1
URINARY_TRACT	OR10A4 →	+0.040	+4.217	.001	.005	3	1
URINARY_TRACT	CCL16 →	+0.010	+4.087	<.001	.009	3	1
LARGE_INTESTINE	SIGLECL1 →	+0.022	+4.977	<.001	.007	3	1
BLOOD_Leukemia	BTBD16 →	+0.092	+3.959	<.001	.005	3	1
BLOOD_Leukemia	RHCG →	+0.122	+3.729	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

MSL1 survival (RNA) · tumor vs normal (RNA) · all MSL1 data types