MSI2

Across TCGA cell cohorts, MSI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,813 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MSI2-associated GO terms across cancer lineages are Copper ion export, Extracellular structure organization, and External encapsulating structure organization. Each is linked with MSI2 in more than 11 cancer types. Because this analysis shows association rather than direction, both MSI2-to-partner and partner-to-MSI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by MSI2-low versus MSI2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSI2→partner) and Y-score (partner→MSI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Copper ion export →	-0.191	-1.135	.001	<.001	3	12
LIVER	Extracellular structure organization →	-0.182	-1.611	.004	.002	3	12
LIVER	External encapsulating structure organization →	-0.179	-1.611	.004	.002	3	12
LIVER	Extracellular matrix organization →	-0.181	-1.611	.004	.002	3	12
PANCREAS	Dentinogenesis →	-1.292	-0.799	.002	.007	3	12
PANCREAS	Negative regulation of chromosome condensation →	+0.146	+1.119	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,813 associations by consensus.

Copper ion export by MSI2 expression — PANCREAS

Explore this box plot interactively →