MSI1

Across TCGA cell cohorts, MSI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,867 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MSI1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Positive regulation of DNA repair, and Transcription initiation at RNA polymerase II promoter. Each is linked with MSI1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MSI1-to-partner and partner-to-MSI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by MSI1-low versus MSI1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSI1→partner) and Y-score (partner→MSI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA-templated transcription initiation →	+0.076	+1.596	<.001	<.001	3	15
BONE	Positive regulation of DNA repair →	+0.089	+2.276	<.001	<.001	3	15
BONE	Transcription initiation at RNA polymerase II promoter →	+0.097	+2.041	<.001	<.001	3	14
BONE	Granzyme-mediated apoptotic signaling pathway →	+0.143	+2.195	<.001	<.001	3	13
LIVER	Renal vesicle formation →	+1.335	+1.588	.003	.009	3	13
LIVER	Metanephric renal vesicle formation →	+1.335	+1.588	.003	.009	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,867 associations by consensus.

DNA-templated transcription initiation by MSI1 expression — STOMACH

Explore this box plot interactively →