MSGN1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MSGN1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MSGN1-associated genes across cancer lineages are DEFB133. Each is linked with MSGN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSGN1-to-partner and partner-to-MSGN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB133 grouped by MSGN1-low versus MSGN1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSGN1→partner) and Y-score (partner→MSGN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSDEFB133 →+0.046+6.357<.001<.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DEFB133 by MSGN1 expression — CNS

Box plot of DEFB133 in MSGN1-low vs MSGN1-high samples in CNS.

Explore this box plot interactively →

Exploration