MSANTD3

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MSANTD3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MSANTD3 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MSANTD3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MSANTD3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

HNSC, LUAD, and LSCC are the cancer types where MSANTD3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSMedianAll0.3250.742.0068view →
LUADDFSMedianII,III,IV0.7970.207.0243view →
LSCCDFSQuartileAll1.0000.746.0172view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MSANTD3–HNSC (DFS)

Kaplan–Meier survival curve for MSANTD3 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration