MSANTD3

Across TCGA patient cohorts, MSANTD3 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MSANTD3-associated genes across cancer lineages are EGFR, GSK-3_pS9, and Ku80. Each is linked with MSANTD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSANTD3-to-partner and partner-to-MSANTD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by MSANTD3-low versus MSANTD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSANTD3→partner) and Y-score (partner→MSANTD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.208	-2.321	.009	.035	3	1
UCEC	GSK-3_pS9 →	-0.412	-3.000	.042	.036	3	1
UCEC	Ku80 →	+0.293	+2.335	.013	.020	3	1
UCEC	MAPK_pT202_Y204 →	-0.535	-2.321	.023	.035	3	1
UCEC	PKC-b-II_pS660 →	-0.380	-3.459	.006	.005	3	1
UCEC	Rictor_pT1135 →	-0.114	-3.459	.027	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

EGFR by MSANTD3 expression — UCEC

Explore this box plot interactively →