MSANTD3-TMEFF1

Across TCGA pan-cancer cohorts, MSANTD3-TMEFF1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MSANTD3-TMEFF1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MSANTD3-TMEFF1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MSANTD3-TMEFF1 is over-expressed in tumor, although a few such as THCA and PRAD show the opposite, repressed pattern.

HNSC, KIRP, and KIRC are the cancer types where MSANTD3-TMEFF1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MSANTD3-TMEFF1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	All	+0.142	<.001	11	view →
KIRP	Female	II,III,IV	+0.292	.001	6	view →
KIRC	Male	All	+0.100	<.001	5	view →
LIHC	All	All	+0.040	<.001	5	view →
CHOL	Male	All	+0.101	.006	4	view →
THCA	All	All	−0.054	.003	4	view →
ESCA	Male	All	+0.102	.021	2	view →
PRAD	All	All	−0.056	.013	2	view →
KICH	Male	IV	+0.090	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MSANTD3-TMEFF1–HNSC

Open the HNSC breakdown →