MSANTD2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MSANTD2 mutation is significantly associated with the RNA expression of many other genes, with 3,216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MSANTD2-associated genes across cancer lineages are MIR6796, RNY1P1, and MARCKSL1P2. Each is linked with MSANTD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSANTD2-to-partner and partner-to-MSANTD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6796 grouped by MSANTD2-low versus MSANTD2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSANTD2→partner) and Y-score (partner→MSANTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMIR6796 →+0.615+5.015<.001.00932
CESCRNY1P1 →+0.206+5.342<.001.00232
UCECMARCKSL1P2 →+0.167+1.946<.001.00832
UCECRN7SKP286 →+0.036+3.668<.001.00932
UCECUSP9YP2 →+0.013+4.673<.001.00132
UCECMIR4445 →+0.139+4.086<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,216 associations by consensus.

MIR6796 by MSANTD2 expression — HNSC

Box plot of MIR6796 in MSANTD2-low vs MSANTD2-high samples in HNSC.

Explore this box plot interactively →

Exploration