MS4A7

Across TCGA cell cohorts, MS4A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MS4A7-associated GO terms across cancer lineages are Endothelial cell morphogenesis, Isoprenoid catabolic process, and Positive regulation of sphingolipid biosynthetic process. Each is linked with MS4A7 in more than 6 cancer types. Because this analysis shows association rather than direction, both MS4A7-to-partner and partner-to-MS4A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cell morphogenesis grouped by MS4A7-low versus MS4A7-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A7→partner) and Y-score (partner→MS4A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Endothelial cell morphogenesis →	-0.696	-0.920	.003	.002	3	7
BLOOD_Lymphoma	Isoprenoid catabolic process →	-1.069	-0.859	<.001	<.001	3	5
BLOOD_Lymphoma	Positive regulation of sphingolipid biosynthetic process →	+0.115	+1.163	<.001	.002	3	5
BLOOD_Lymphoma	Positive regulation of ceramide biosynthetic process →	+0.115	+1.163	<.001	.002	3	5
SKIN	Growth plate cartilage development →	-0.168	-0.650	<.001	<.001	3	5
BREAST	Regulation of triglyceride storage →	-0.176	-0.856	.002	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Endothelial cell morphogenesis by MS4A7 expression — BLOOD_Lymphoma

Explore this box plot interactively →