MS4A5

Across TCGA patient cohorts, MS4A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,456 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MS4A5-associated GO terms across cancer lineages are Protein methylation, Protein-DNA complex assembly, and Transport along microtubule. Each is linked with MS4A5 in more than 11 cancer types. Because this analysis shows association rather than direction, both MS4A5-to-partner and partner-to-MS4A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein methylation grouped by MS4A5-low versus MS4A5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A5→partner) and Y-score (partner→MS4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein methylation →	+0.066	+0.109	<.001	<.001	3	12
STAD	Protein-DNA complex assembly →	+0.067	+0.134	<.001	<.001	3	11
STAD	Transport along microtubule →	+0.061	+0.126	<.001	<.001	3	11
STAD	Endosomal transport →	+0.072	+0.117	<.001	<.001	3	11
STAD	Peptidyl-lysine methylation →	+0.064	+0.128	<.001	<.001	3	11
STAD	Peptidyl-lysine modification →	+0.072	+0.127	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,456 associations by consensus.

Protein methylation by MS4A5 expression — STAD

Explore this box plot interactively →