MS4A5

Across TCGA cell cohorts, MS4A5 RNA expression is significantly associated with the mutation status of many other genes, with 28 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MS4A5-associated genes across cancer lineages are MYBPH, GALNT14, and CCDC110. Each is linked with MS4A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A5-to-partner and partner-to-MS4A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYBPH grouped by MS4A5-low versus MS4A5-high in BONE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A5→partner) and Y-score (partner→MS4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	MYBPH →	+4.169	+0.084	.008	<.001	3	1
BLOOD_Leukemia	GALNT14 →	+4.384	+0.049	.006	<.001	3	1
BLOOD_Leukemia	CCDC110 →	+4.384	+0.049	.006	<.001	3	1
BLOOD_Leukemia	PTDSS2 →	+5.969	+0.082	.001	<.001	3	1
BLOOD_Leukemia	INPP5F →	+4.969	+0.061	.003	<.001	3	1
BLOOD_Leukemia	SLC26A6 →	+3.969	+0.040	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

MYBPH by MS4A5 expression — BONE

Explore this box plot interactively →