Across TCGA cell cohorts, MS4A4E RNA expression is significantly associated with the go_rna of many other GO terms, with 1,764 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MS4A4E-associated GO terms across cancer lineages are Positive regulation of cytoplasmic translation, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with MS4A4E in more than 4 cancer types. Because this analysis shows association rather than direction, both MS4A4E-to-partner and partner-to-MS4A4E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A4E→partner) and Y-score (partner→MS4A4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of cytoplasmic translation →	+0.096	+0.090	<.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.070	+0.242	.002	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Electron transport coupled proton transport →	+0.070	+0.242	.002	<.001	3	5
OVARY	Synaptic vesicle recycling →	+0.073	+0.020	<.001	<.001	3	5
BLOOD_Leukemia	sno(s)RNA 3'-end processing →	+0.056	+1.030	<.001	<.001	3	5
BLOOD_Leukemia	U4 snRNA 3'-end processing →	+0.109	+1.497	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,764 associations by consensus.

Exploration

MS4A4E survival (RNA) · tumor vs normal (RNA) · all MS4A4E data types