MS4A3

Across TCGA patient cohorts, MS4A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,687 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MS4A3-associated GO terms across cancer lineages are Regulation of leukocyte adhesion to vascular endothelial cell, Mucopolysaccharide metabolic process, and Cell-matrix adhesion. Each is linked with MS4A3 in more than 17 cancer types. Because this analysis shows association rather than direction, both MS4A3-to-partner and partner-to-MS4A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of leukocyte adhesion to vascular endothelial cell grouped by MS4A3-low versus MS4A3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A3→partner) and Y-score (partner→MS4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of leukocyte adhesion to vascular endothelial cell →	+0.077	+0.323	<.001	.001	3	18
ESCA	Mucopolysaccharide metabolic process →	+0.042	+0.090	<.001	<.001	3	18
ESCA	Cell-matrix adhesion →	+0.078	+0.144	<.001	<.001	3	18
ESCA	Regulation of epithelial cell migration →	+0.054	+0.081	<.001	.001	3	18
ESCA	Myeloid cell activation involved in immune response →	+0.050	+0.080	<.001	.001	3	18
ESCA	Positive regulation of interleukin-2 production →	+0.091	+0.138	<.001	.003	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,687 associations by consensus.

Regulation of leukocyte adhesion to vascular endothelial cell by MS4A3 expression — STAD

Explore this box plot interactively →