MS4A2

Across TCGA patient cohorts, MS4A2 protein abundance is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MS4A2-associated genes across cancer lineages are ESS2, DHX40, and HLF. Each is linked with MS4A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A2-to-partner and partner-to-MS4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MS4A2 versus ESS2 in LUAD, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A2→partner) and Y-score (partner→MS4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ESS2 →	-0.590	-0.671	.009	.006	3	1
LUAD	DHX40 →	-0.810	-0.842	<.001	<.001	3	1
LUAD	HLF →	-2.286	-0.670	<.001	.003	3	1
LUAD	APOA5 →	-0.079	-0.547	.003	<.001	3	1
LUAD	PEX7 →	-0.687	-0.610	.001	.005	3	1
LUAD	FANCL →	-0.471	-0.482	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

MS4A2 vs ESS2 — LUAD

Explore this scatter interactively →