MS4A2

Across TCGA patient cohorts, MS4A2 protein abundance is significantly associated with the protein abundance of many other proteins, with 299 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MS4A2-associated proteins across cancer lineages are ALKBH8, GRHL2_T164, and KAZN_S346. Each is linked with MS4A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A2-to-partner and partner-to-MS4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MS4A2 versus ALKBH8 in LUAD, with a Pearson correlation of -0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A2→partner) and Y-score (partner→MS4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ALKBH8 →	-0.360	-0.661	<.001	.006	3	1
LUAD	GRHL2_T164 →	-0.855	-0.520	<.001	.002	3	1
LUAD	KAZN_S346 →	-1.244	-0.593	<.001	.002	3	1
LUAD	ARHGAP31_S1273 →	+0.741	+0.995	<.001	.001	3	1
LUAD	SLC15A3 →	+0.388	+0.577	.001	.002	3	1
LUAD	TSPAN1 →	+2.755	+0.785	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 299 associations by consensus.

MS4A2 vs ALKBH8 — LUAD

Explore this scatter interactively →