MS4A2

Across TCGA cell cohorts, MS4A2 RNA expression is significantly associated with the RNA expression of many other genes, with 3,612 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MS4A2-associated genes across cancer lineages are COL6A5, LRRC52, and OR6V1. Each is linked with MS4A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MS4A2-to-partner and partner-to-MS4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MS4A2 versus COL6A5 in BLOOD_Leukemia, with a Pearson correlation of 0.50.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A2→partner) and Y-score (partner→MS4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	COL6A5 →	+0.636	+1.118	<.001	<.001	3	3
LUNG_NSCLC_LUAD	LRRC52 →	+0.864	+0.010	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR6V1 →	+0.108	+0.008	<.001	.008	3	3
BLOOD_Leukemia	NDUFV3 →	+0.584	+0.910	<.001	<.001	3	2
SKIN	KRTAP21-2 →	+0.101	+0.079	.001	.004	3	2
UPPER_AERODIGESTIVE_TRACT	OR2T2 →	+0.097	+0.013	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,612 associations by consensus.

MS4A2 vs COL6A5 — BLOOD_Leukemia

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