MS4A2

Across TCGA cell cohorts, MS4A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,592 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MS4A2-associated GO terms across cancer lineages are Negative regulation of protein catabolic process, Protein-lipid complex assembly, and Plasma lipoprotein particle assembly. Each is linked with MS4A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MS4A2-to-partner and partner-to-MS4A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein catabolic process grouped by MS4A2-low versus MS4A2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A2→partner) and Y-score (partner→MS4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of protein catabolic process →	+0.044	+1.039	<.001	<.001	3	4
BLOOD_Leukemia	Protein-lipid complex assembly →	+0.151	+1.231	<.001	<.001	3	3
BLOOD_Leukemia	Plasma lipoprotein particle assembly →	+0.155	+1.431	<.001	<.001	3	3
CNS	Positive regulation of transmission of nerve impulse →	-1.168	-0.012	<.001	.006	3	3
BLOOD_Leukemia	SRP-dependent cotranslational protein targeting to membrane →	+0.089	+1.042	<.001	<.001	3	3
BLOOD_Leukemia	Response to lead ion →	+0.085	+1.110	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,592 associations by consensus.

Negative regulation of protein catabolic process by MS4A2 expression — BLOOD_Leukemia

Explore this box plot interactively →