MS4A2

Across TCGA cell cohorts, MS4A2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MS4A2-associated genes across cancer lineages are ELOA3DP and OR6Q1. Each is linked with MS4A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A2-to-partner and partner-to-MS4A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by MS4A2-low versus MS4A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A2→partner) and Y-score (partner→MS4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELOA3DP →	+0.026	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ELOA3DP by MS4A2 expression — LARGE_INTESTINE

Explore this box plot interactively →