Across TCGA patient cohorts, MS4A13 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MS4A13-associated genes across cancer lineages are Class-switched memory B-cells, Endothelial cells, and Erythrocytes. Each is linked with MS4A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A13-to-partner and partner-to-MS4A13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A13→partner) and Y-score (partner→MS4A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Class-switched memory B-cells →	-0.052	-2.906	.032	.002	3	1
UCEC	Endothelial cells →	-0.038	-2.179	.019	.011	3	1
UCEC	Erythrocytes →	+0.027	+3.180	.011	.010	3	1
UCEC	lymphatic Endothelial cells →	-0.022	-1.959	.031	.031	3	1
UCEC	Mesangial cells →	-0.048	-2.211	.003	.011	3	1
UCEC	Basophils →	+0.157	+1.700	.029	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

MS4A13 survival (RNA) · tumor vs normal (RNA) · all MS4A13 data types