MS4A1

Across TCGA cell cohorts, MS4A1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,024 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MS4A1-associated genes across cancer lineages are CYBRD1, TIMP2, and MARK1. Each is linked with MS4A1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MS4A1-to-partner and partner-to-MS4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MS4A1 versus CYBRD1 in SKIN, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A1→partner) and Y-score (partner→MS4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CYBRD1 →	+2.128	+2.138	<.001	<.001	3	11
OESOPHAGUS	TIMP2 →	+3.812	+1.908	.002	.005	2	6
LUNG_NSCLC_LUSC	MARK1 →	-2.283	-2.501	.001	<.001	3	4
LUNG_NSCLC_LUSC	SUCLG2 →	+1.067	+2.286	.004	.004	3	4
CNS	BCL7C →	+0.677	+1.391	<.001	<.001	3	4
URINARY_TRACT	PARD3B →	+1.237	+2.005	.003	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

MS4A1 vs CYBRD1 — SKIN

Explore this scatter interactively →