MRTO4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRTO4 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRTO4-associated genes across cancer lineages are Neutrophils. Each is linked with MRTO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRTO4-to-partner and partner-to-MRTO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by MRTO4-low versus MRTO4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRTO4→partner) and Y-score (partner→MRTO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNeutrophils →+0.015+2.166.008.04031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Neutrophils by MRTO4 expression — UCEC

Box plot of Neutrophils in MRTO4-low vs MRTO4-high samples in UCEC.

Explore this box plot interactively →

Exploration