Across TCGA patient cohorts, MRTFB protein abundance is significantly associated with the RNA expression of many other genes, with 13,452 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MRTFB-associated genes across cancer lineages are EARS2, ELOB, and DNAJA3. Each is linked with MRTFB in more than 6 cancer types. Because this analysis shows association rather than direction, both MRTFB-to-partner and partner-to-MRTFB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRTFB→partner) and Y-score (partner→MRTFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EARS2 →	+0.666	+0.605	<.001	<.001	3	6
HNSC	ELOB →	+1.016	+0.177	.006	.005	3	6
OV	DNAJA3 →	+0.691	+0.406	<.001	<.001	3	6
LSCC	RSL1D1 →	+0.393	+0.181	<.001	<.001	3	6
BRCA	PDXDC1 →	+0.872	+0.554	<.001	<.001	3	6
HNSC	TMEM186 →	+0.513	+0.228	.005	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,452 associations by consensus.

Exploration

MRTFB survival (RNA) · tumor vs normal (RNA) · all MRTFB data types