MRTFB

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRTFB mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRTFB-associated genes across cancer lineages are 14-3-3_epsilon, Paxillin, and PI3K-p110-a. Each is linked with MRTFB in more than 1 cancer types. Because this analysis shows association rather than direction, both MRTFB-to-partner and partner-to-MRTFB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRTFB→partner) and Y-score (partner→MRTFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCM14-3-3_epsilon →+0.160+1.824.001.01532
SKCMPaxillin →+0.442+2.584.008.01032
SKCMPI3K-p110-a →+0.126+2.476.046.00932
UCECBak →+0.277+2.584.002.01032
SKCMHER2 →+0.276+1.807.017.02631
SKCMAcetyl-a-Tubulin-Lys40 →+0.732+2.321.001.03231
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration