Across TCGA cell cohorts, MRTFB RNA expression is significantly associated with the go_rna of many other GO terms, with 5,121 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRTFB-associated GO terms across cancer lineages are Protein polyubiquitination, Regulation of organelle assembly, and Symbiont-mediated disruption of host cell PML body. Each is linked with MRTFB in more than 17 cancer types. Because this analysis shows association rather than direction, both MRTFB-to-partner and partner-to-MRTFB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRTFB→partner) and Y-score (partner→MRTFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein polyubiquitination →	+0.062	+0.992	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.046	+0.872	<.001	.002	3	17
BREAST	Symbiont-mediated disruption of host cell PML body →	+0.092	+0.841	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of nucleotide-excision repair →	+0.130	+1.205	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.053	+1.115	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.081	+1.166	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,121 associations by consensus.

Exploration

MRTFB survival (RNA) · tumor vs normal (RNA) · all MRTFB data types