Across TCGA patient cohorts, MRTFA protein abundance is significantly associated with the RNA expression of many other genes, with 9,100 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRTFA-associated genes across cancer lineages are SMG5, TMEM97, and GALNT12. Each is linked with MRTFA in more than 3 cancer types. Because this analysis shows association rather than direction, both MRTFA-to-partner and partner-to-MRTFA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRTFA→partner) and Y-score (partner→MRTFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMG5 →	-0.440	-0.236	.007	.009	3	4
HNSC	TMEM97 →	-1.217	-0.420	<.001	<.001	3	3
COAD	GALNT12 →	-1.101	-1.513	<.001	.001	3	3
LUAD	C12orf76 →	-0.445	-0.188	<.001	<.001	3	3
HNSC	ASH1L-AS1 →	-0.661	-0.328	<.001	<.001	3	3
OV	STPG3-AS1 →	-0.437	-0.439	.006	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,100 associations by consensus.

Exploration

MRTFA survival (RNA) · tumor vs normal (RNA) · all MRTFA data types