Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, MRTFA mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible MRTFA-associated genes across cancer lineages are ERK2, MSH6, and VHL. Each is linked with MRTFA in more than 1 cancer types. Because this analysis shows association rather than direction, both MRTFA-to-partner and partner-to-MRTFA results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (MRTFA→partner) and Y-score (partner→MRTFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.