MRPS9

Across TCGA pan-cancer cohorts, MRPS9 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MRPS9 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MRPS9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPS9 expression acts as an unfavorable survival marker, although some lineages such as LSCC and COAD show a favorable association.

LSCC, COAD, and PDAC are the cancer types where MRPS9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.859	0.507	.002	13	view →
COAD	DFS	Median	All	1.000	0.923	.019	12	view →
PDAC	OS	Median	IV	0.491	0.836	.024	9	view →
LUAD	DFS	Median	III,IV	0.722	0.285	.017	4	view →
HNSC	DFS	Median	III,IV	0.721	0.493	.012	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MRPS9–LSCC (DFS)

Open the LSCC breakdown →