MRPS9

Across TCGA cell cohorts, MRPS9 mutation is significantly associated with the RNA expression of many other genes, with 159 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPS9-associated genes across cancer lineages are SLC25A17, USP14, and GRIN2D. Each is linked with MRPS9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS9-to-partner and partner-to-MRPS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A17 grouped by MRPS9-low versus MRPS9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS9→partner) and Y-score (partner→MRPS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC25A17 →	+0.691	+3.364	<.001	.002	3	1
LARGE_INTESTINE	USP14 →	+0.741	+3.087	.001	.006	3	1
LARGE_INTESTINE	GRIN2D →	-1.521	-3.278	<.001	.006	3	1
LARGE_INTESTINE	LRRC59 →	+0.644	+3.067	.001	.009	3	1
LARGE_INTESTINE	UGDH →	+0.928	+3.451	.002	.002	3	1
LARGE_INTESTINE	UTP18 →	+0.453	+3.624	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

SLC25A17 by MRPS9 expression — LARGE_INTESTINE

Explore this box plot interactively →