MRPS9

Across TCGA cell cohorts, MRPS9 mutation is significantly associated with the mutation status of many other genes, with 3,270 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPS9-associated genes across cancer lineages are VPS39, DGKB, and RANBP6. Each is linked with MRPS9 in more than 3 cancer types. Because this analysis shows association rather than direction, both MRPS9-to-partner and partner-to-MRPS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VPS39 grouped by MRPS9-low versus MRPS9-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS9→partner) and Y-score (partner→MRPS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	VPS39 →	+5.392	+5.392	.004	.004	1	4
UPPER_AERODIGESTIVE_TRACT	DGKB →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	RANBP6 →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	ABL2 →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	NCK1 →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	TAOK1 →	+4.392	+4.954	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,270 associations by consensus.

VPS39 by MRPS9 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →