MRPS6P4

Across TCGA pan-cancer cohorts, MRPS6P4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MRPS6P4 data layer.

The strongest signal is observed in thymoma (THYM), where higher MRPS6P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPS6P4 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

THYM, UVM, and BLCA are the cancer types where MRPS6P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.039	0.928	<.001	72	view →
UVM	OS	Tertile	II,III,IV	0.218	0.718	.006	72	view →
BLCA	DFS	Tertile	III,IV	0.208	0.580	<.001	66	view →
KIRC	DFS	Tertile	IV	0.141	0.631	<.001	54	view →
READ	DFS	Tertile	III,IV	0.182	0.745	.007	36	view →
LIHC	OS	Tertile	III,IV	0.051	0.616	<.001	27	view →
LGG	OS	Tertile	All	0.171	0.527	.001	21	view →
OV	OS	Tertile	II,III,IV	0.634	0.849	.035	18	view →
SARC	OS	Tertile	All	0.111	0.517	.001	18	view →
UCEC	DFS	Tertile	All	0.793	0.898	.039	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.375	.043	12	view →
COAD	DFS	Tertile	II,III,IV	0.405	0.746	.032	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

MRPS6P4–THYM (OS)

Open the THYM breakdown →