MRPS6P2

Across TCGA pan-cancer cohorts, MRPS6P2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MRPS6P2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MRPS6P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPS6P2 expression acts as an unfavorable survival marker, although some lineages such as OV and STAD show a favorable association.

UVM, THYM, and UCEC are the cancer types where MRPS6P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.037	0.835	<.001	54	view →
THYM	DFS	Tertile	II,III,IV	0.621	0.933	.009	36	view →
UCEC	OS	Tertile	III,IV	0.723	0.853	.011	36	view →
KICH	DFS	Tertile	III,IV	0.035	0.772	.021	30	view →
OV	OS	Median	III,IV	0.388	0.272	.004	24	view →
KIRC	DFS	Quartile	IV	0.149	0.376	.001	22	view →
STAD	OS	Quartile	III,IV	0.690	0.506	.014	20	view →
BLCA	OS	Tertile	IV	0.139	0.602	<.001	18	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	18	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	18	view →
PRAD	OS	Tertile	All	0.756	0.909	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MRPS6P2–UVM (OS)

Open the UVM breakdown →