MRPS5

Across TCGA cell cohorts, MRPS5 mutation is significantly associated with the drug of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPS5-associated genes across cancer lineages are Mirin, GSK1070916, and NSC-207895. Each is linked with MRPS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS5-to-partner and partner-to-MRPS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by MRPS5-low versus MRPS5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS5→partner) and Y-score (partner→MRPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.472	+2.646	.011	.047	3	1
LARGE_INTESTINE	GSK1070916 →	+0.635	+2.655	.033	.044	3	1
LARGE_INTESTINE	NSC-207895 →	+0.432	+2.786	.047	.037	3	1
LARGE_INTESTINE	Venotoclax →	+0.171	+2.722	.031	.040	3	1
LARGE_INTESTINE	Ara-G →	+0.235	+2.722	.004	.040	3	1
LARGE_INTESTINE	ETP-45835 →	+0.263	+2.652	.029	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Mirin by MRPS5 expression — LARGE_INTESTINE

Explore this box plot interactively →