mitochondrial ribosomal protein S36 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored MRPS36P1 profile across patient tissues and cancer cell-line models. MRPS36P1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MRPS36P1 is differentially expressed in 6, with the highest sampling consensus in STAD. Additionally, MRPS36P1 RNA expression shows 6,667 significant protein co-abundance associations, with the highest sampling consensus in OV. Together, these results highlight UVM, STAD, and OV as cancer lineages where MRPS36P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MRPS36P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MRPS36P1 survival associations across molecular data types. MRPS36P1 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MRPS36P1 RNA expression–survival associations across cancer types. High MRPS36P1 expression shows unfavorable associations in UVM, OV, KICH and DLBC, but favorable associations in CESC and HNSC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify UVM as the clearest survival context for MRPS36P1 RNA expression.
This table summarizes MRPS36P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MRPS36P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MRPS36P1 shows lower tumor expression in STAD and KIRC and higher tumor expression in COAD, LUAD, KICH and THCA. The STAD box plot shows higher MRPS36P1 RNA expression in normal versus tumor tissue (log2 FC = −0.615, t-test p = .001).
This table shows molecular features associated with MRPS36P1 in patient tissues and cancer cell lines. In patient samples, MRPS36P1 shows the broadest associations at the RNA and protein expression levels, with OV recurring as the lineage with the largest associated feature set.