MRPS36

Across TCGA pan-cancer cohorts, MRPS36 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated MRPS36 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MRPS36 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MRPS36 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and LUAD are the cancer types where MRPS36 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.974	0.692	.002	14	view →
UCEC	OS	Median	II,III,IV	1.000	0.666	.025	8	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	8	view →
GBM	OS	Quartile	All	0.886	0.721	.008	7	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.902	.041	6	view →
CCRCC	DFS	Tertile	II,III,IV	0.378	0.725	.017	5	view →
HNSC	DFS	Median	III,IV	1.000	0.939	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MRPS36–PDAC (OS)

Open the PDAC breakdown →