MRPS35

Across TCGA cell cohorts, MRPS35 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,470 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MRPS35-associated GO terms across cancer lineages are Mitochondrial translation, Ubiquinone biosynthetic process, and Quinone biosynthetic process. Each is linked with MRPS35 in more than 10 cancer types. Because this analysis shows association rather than direction, both MRPS35-to-partner and partner-to-MRPS35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by MRPS35-low versus MRPS35-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS35→partner) and Y-score (partner→MRPS35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial translation →	+0.088	+0.424	.005	.005	3	11
LARGE_INTESTINE	Ubiquinone biosynthetic process →	+0.090	+0.763	<.001	<.001	3	11
LARGE_INTESTINE	Quinone biosynthetic process →	+0.090	+0.763	<.001	<.001	3	11
BREAST	Mitochondrial ribosome assembly →	+0.090	+1.078	<.001	<.001	3	10
STOMACH	Quinone metabolic process →	+0.092	+1.277	.002	<.001	3	9
CNS	tRNA splicing, via endonucleolytic cleavage and ligation →	+0.082	+0.471	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,470 associations by consensus.

Mitochondrial translation by MRPS35 expression — BONE

Explore this box plot interactively →