MRPS31P5

Across TCGA pan-cancer cohorts, MRPS31P5 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MRPS31P5 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MRPS31P5 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPS31P5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UCS, and KIRC are the cancer types where MRPS31P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.447	0.289	<.001	73	view →
UCS	DFS	Median	IV	0.952	0.367	.001	46	view →
KIRC	OS	Tertile	All	0.895	0.838	.005	41	view →
LUSC	OS	Median	II,III,IV	0.215	0.666	<.001	39	view →
OV	OS	Median	III,IV	0.263	0.362	.003	36	view →
CESC	DFS	Quartile	All	0.656	0.840	.009	32	view →
READ	OS	Median	II,III,IV	0.793	0.453	<.001	32	view →
LAML	DFS	Median	All	0.520	0.250	<.001	24	view →
BRCA	OS	Tertile	III,IV	0.963	0.845	.005	19	view →
LUAD	OS	Median	All	0.855	0.773	.003	13	view →
UCEC	DFS	Quartile	IV	1.000	0.364	.013	12	view →
PAAD	OS	Median	II,III,IV	0.659	0.510	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MRPS31P5–HNSC (DFS)

Open the HNSC breakdown →