MRPS31P4

Across TCGA pan-cancer cohorts, MRPS31P4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MRPS31P4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MRPS31P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MRPS31P4 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

KIRC, UCS, and BRCA are the cancer types where MRPS31P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.734	0.554	<.001	93	view →
UCS	DFS	Quartile	II,III,IV	0.698	0.170	.007	54	view →
BRCA	DFS	Median	III,IV	0.582	0.373	<.001	50	view →
LAML	DFS	Median	All	0.553	0.216	.001	36	view →
COAD	OS	Median	IV	0.925	0.223	<.001	34	view →
READ	OS	Median	II,III,IV	0.980	0.833	.001	29	view →
KIRP	DFS	Median	All	0.956	0.865	.004	28	view →
OV	OS	Median	II,III,IV	0.263	0.371	<.001	28	view →
CESC	DFS	Quartile	All	0.386	0.675	.001	26	view →
LUSC	DFS	Tertile	III,IV	0.528	1.000	.002	19	view →
HNSC	OS	Quartile	All	0.631	0.833	.011	15	view →
GBM	DFS	Median	All	0.390	0.189	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MRPS31P4–KIRC (OS)

Open the KIRC breakdown →