MRPS31P2

Across TCGA pan-cancer cohorts, MRPS31P2 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MRPS31P2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MRPS31P2 RNA is repressed in tumor relative to normal tissue. In most cancer types MRPS31P2 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, HNSC, and KICH are the cancer types where MRPS31P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPS31P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.132	<.001	7	view →
HNSC	All	III,IV	+0.087	.005	7	view →
KICH	All	All	−0.215	<.001	6	view →
BRCA	Female	All	−0.083	.004	6	view →
LUAD	All	All	+0.233	<.001	4	view →
KIRC	Male	II,III,IV	−0.113	.003	4	view →
BLCA	Male	All	+0.228	.019	3	view →
KIRP	Female	II,III,IV	−0.176	.003	3	view →
LUSC	Male	All	+0.070	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MRPS31P2–THCA

Open the THCA breakdown →