MRPS31

Across TCGA cell cohorts, MRPS31 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,844 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPS31-associated GO terms across cancer lineages are Mitochondrial translational termination, Sister chromatid biorientation, and Cajal body organization. Each is linked with MRPS31 in more than 17 cancer types. Because this analysis shows association rather than direction, both MRPS31-to-partner and partner-to-MRPS31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translational termination grouped by MRPS31-low versus MRPS31-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS31→partner) and Y-score (partner→MRPS31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial translational termination →	+0.128	+0.726	<.001	<.001	3	18
LUNG_SCLC	Sister chromatid biorientation →	+0.192	+0.766	<.001	<.001	3	15
BONE	Cajal body organization →	+0.115	+0.609	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Sister chromatid cohesion →	+0.076	+0.700	.006	.003	3	12
SKIN	Translational termination →	+0.080	+0.507	<.001	<.001	3	12
BONE	Mitochondrial translation →	+0.092	+0.710	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,844 associations by consensus.

Mitochondrial translational termination by MRPS31 expression — LUNG_SCLC

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