MRPS30

Across TCGA cell cohorts, MRPS30 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPS30-associated genes across cancer lineages are OR2T35, IL31, and POLR1C. Each is linked with MRPS30 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS30-to-partner and partner-to-MRPS30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T35 grouped by MRPS30-low versus MRPS30-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS30→partner) and Y-score (partner→MRPS30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2T35 →	+0.012	+2.977	<.001	.006	3	2
LUNG_NSCLC_LUAD	IL31 →	+0.045	+4.212	<.001	.007	3	1
LARGE_INTESTINE	POLR1C →	+0.472	+3.067	.005	.009	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR2T35 by MRPS30 expression — LARGE_INTESTINE

Explore this box plot interactively →