MRPS28

Across TCGA pan-cancer cohorts, MRPS28 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MRPS28 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRPS28 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPS28 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, CCRCC, and LUAD are the cancer types where MRPS28 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.887	.022	30	view →
CCRCC	OS	Median	IV	0.123	0.785	.009	20	view →
LUAD	OS	Quartile	III,IV	1.000	0.296	.022	8	view →
GBM	OS	Tertile	All	0.909	0.815	.031	3	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	3	view →
LSCC	DFS	Median	II,III,IV	1.000	0.571	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MRPS28–COAD (DFS)

Open the COAD breakdown →