MRPS24

Across TCGA pan-cancer cohorts, MRPS24 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated MRPS24 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MRPS24 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MRPS24 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, HNSC, and LUAD are the cancer types where MRPS24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.948	0.643	.005	24	view →
HNSC	DFS	Quartile	All	0.616	0.837	.009	17	view →
LUAD	DFS	Quartile	III,IV	0.875	0.344	.008	13	view →
OV	DFS	Median	All	0.900	0.657	.013	8	view →
UCEC	DFS	Tertile	II,III,IV	0.318	0.884	.036	8	view →
CCRCC	DFS	Median	III,IV	0.396	0.815	.010	4	view →
PDAC	DFS	Median	All	0.353	0.534	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MRPS24–LSCC (OS)

Open the LSCC breakdown →