MRPS23

Across TCGA patient cohorts, MRPS23 protein abundance is significantly associated with the RNA expression of many other genes, with 16,224 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS23-associated genes across cancer lineages are ZEB2, MFAP4, and NEGR1. Each is linked with MRPS23 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPS23-to-partner and partner-to-MRPS23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS23 versus ZEB2 in HNSC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS23→partner) and Y-score (partner→MRPS23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZEB2 →	-0.681	-0.264	<.001	<.001	3	8
OV	MFAP4 →	-1.347	-0.401	.003	<.001	3	6
BRCA	NEGR1 →	-0.999	-0.492	<.001	<.001	3	6
HNSC	GAS1RR →	-0.590	-0.199	.002	.009	2	7
BRCA	EPS15 →	-0.389	-0.345	<.001	<.001	3	6
BRCA	LRRC4C →	-0.889	-0.252	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,224 associations by consensus.

MRPS23 vs ZEB2 — HNSC

Explore this scatter interactively →