MRPS23

Across TCGA patient cohorts, MRPS23 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS23-associated genes across cancer lineages are Skeletal muscle and Th2 cells. Each is linked with MRPS23 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS23-to-partner and partner-to-MRPS23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal muscle grouped by MRPS23-low versus MRPS23-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS23→partner) and Y-score (partner→MRPS23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Skeletal muscle →	+0.057	+3.010	.023	.020	3	1
UCEC	Th2 cells →	+0.334	+2.815	.001	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Skeletal muscle by MRPS23 expression — UCEC

Explore this box plot interactively →