MRPS21P9

Across TCGA pan-cancer cohorts, MRPS21P9 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MRPS21P9’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MRPS21P9 RNA is repressed in tumor relative to normal tissue. In most cancer types MRPS21P9 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and BRCA are the cancer types where MRPS21P9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPS21P9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.093	<.001	9	view →
THCA	Female	All	−0.252	<.001	5	view →
BRCA	All	All	+0.195	.022	4	view →
BLCA	All	All	+0.172	.023	4	view →
LIHC	Male	All	+0.076	.032	4	view →
KIRP	Male	All	−0.081	.020	3	view →
COAD	All	III,IV	−0.237	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MRPS21P9–KIRC

Open the KIRC breakdown →