MRPS21P5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MRPS21P5 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MRPS21P5 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MRPS21P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MRPS21P5 expression acts as an unfavorable survival marker, although some lineages such as UCS and GBM show a favorable association.

LUAD, ACC, and STAD are the cancer types where MRPS21P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileIV0.3420.893<.00151view →
ACCOSTertileII,III,IV0.1350.658.01027view →
STADDFSTertileAll0.1670.422.01118view →
COADOSTertileIV0.1200.681.00318view →
THCAOSTertileIV0.6261.000.00218view →
DLBCDFSTertileIII,IV0.1370.790<.00118view →
SKCMDFSTertileIV0.0360.433<.00112view →
THYMDFSTertileII,III,IV0.2330.768.0109view →
UCSOSTertileAll0.7970.295.0476view →
UCECOSTertileIII,IV0.6840.840.0266view →
GBMOSTertileAll0.6860.395.0203view →
LIHCOSTertileII,III,IV0.4460.710.0413view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration