MRPS21

Across TCGA patient cohorts, MRPS21 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,718 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MRPS21-associated proteins across cancer lineages are RPRD2, ANP32E, and TIPRL. Each is linked with MRPS21 in more than 5 cancer types. Because this analysis shows association rather than direction, both MRPS21-to-partner and partner-to-MRPS21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS21 versus RPRD2 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS21→partner) and Y-score (partner→MRPS21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPRD2 →	+0.328	+0.291	<.001	<.001	3	6
BRCA	ANP32E →	+0.448	+0.531	<.001	<.001	3	6
GBM	TIPRL →	+0.187	+0.222	.001	.001	3	6
BRCA	GATAD2B →	+0.397	+0.735	<.001	<.001	3	6
LSCC	RRBP1 →	-0.544	-0.661	<.001	.001	3	5
LSCC	TRRAP →	+0.282	+0.677	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,718 associations by consensus.

MRPS21 vs RPRD2 — GBM

Explore this scatter interactively →