MRPS21

Across TCGA patient cohorts, MRPS21 protein abundance is significantly associated with the RNA expression of many other genes, with 12,685 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS21-associated genes across cancer lineages are VNN2, ZEB2, and TNFSF8. Each is linked with MRPS21 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPS21-to-partner and partner-to-MRPS21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS21 versus VNN2 in COAD, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS21→partner) and Y-score (partner→MRPS21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VNN2 →	-0.939	-0.410	<.001	<.001	3	8
COAD	ZEB2 →	-0.654	-0.355	<.001	.003	3	7
COAD	TNFSF8 →	-0.661	-0.352	.002	.007	3	6
BRCA	CARD8-AS1 →	-0.641	-0.388	<.001	<.001	3	6
LSCC	CASS4 →	-0.571	-0.423	<.001	<.001	3	6
OV	CNRIP1 →	-0.744	-0.589	.007	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,685 associations by consensus.

MRPS21 vs VNN2 — COAD

Explore this scatter interactively →