MRPS21

Across TCGA cell cohorts, MRPS21 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,720 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPS21-associated GO terms across cancer lineages are NADH dehydrogenase complex assembly, Mitochondrial respiratory chain complex I assembly, and Wound healing. Each is linked with MRPS21 in more than 9 cancer types. Because this analysis shows association rather than direction, both MRPS21-to-partner and partner-to-MRPS21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NADH dehydrogenase complex assembly grouped by MRPS21-low versus MRPS21-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS21→partner) and Y-score (partner→MRPS21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	NADH dehydrogenase complex assembly →	+0.102	+1.132	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Mitochondrial respiratory chain complex I assembly →	+0.102	+1.132	<.001	<.001	3	10
CNS	Wound healing →	-0.101	-0.708	<.001	.001	3	9
LUNG_NSCLC_LUSC	Tetrapyrrole biosynthetic process →	+0.132	+1.081	.001	.001	3	9
LUNG_NSCLC_LUAD	Iron-sulfur cluster assembly →	+0.066	+0.740	<.001	.001	3	9
LUNG_NSCLC_LUAD	Metallo-sulfur cluster assembly →	+0.066	+0.740	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,720 associations by consensus.

NADH dehydrogenase complex assembly by MRPS21 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →